FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ARA54
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RNF14. AA range:361-410
特异性
ARA54 Polyclonal Antibody detects endogenous levels of ARA54 protein.
基因名称
RNF14
蛋白名称
E3 ubiquitin-protein ligase RNF14
别名
RNF14;ARA54;HRIHFB2038;E3 ubiquitin-protein ligase RNF14;Androgen receptor-associated protein 54;HFB30;RING finger protein 14;Triad2 protein
Organism-1
Human
基因ID-1
9604
SwissProt-1
Q9UBS8
Organism-2
Mouse
基因ID-2
56736
SwissProt-2
Q9JI90
背景
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011],
细胞定位
Cytoplasm . Nucleus .
