- 产品信息
商品描述
靶点-Target
APS
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
67kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human APS.
特异性
APS Polyclonal Antibody detects endogenous levels of APS protein.
基因名称
SH2B2
蛋白名称
SH2B adapter protein 2
别名
SH2B2;APS;SH2B adapter protein 2;Adapter protein with pleckstrin homology and Src homology 2 domains;SH2 and PH domain-containing adapter protein APS
Organism-1
Human
基因ID-1
10603
SwissProt-1
O14492
Organism-2
Mouse
基因ID-2
23921
SwissProt-2
Q9JID9
Organism-3
Rat
基因ID-3
114203
SwissProt-3
Q9Z200
背景
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009],
细胞定位
Cytoplasm . Cell membrane . Cytoplasmic before PDGF stimulation. After PDGF stimulation, localized at the cell membrane and peripheral region.





