FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
APPL1
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human APPL1. AA range:121-170
特异性
APPL1 Polyclonal Antibody detects endogenous levels of APPL1 protein.
基因名称
APPL1
蛋白名称
DCC-interacting protein 13-alpha
别名
APPL1;APPL;DIP13A;KIAA1428;DCC-interacting protein 13-alpha;Dip13-alpha;Adapter protein containing PH domain;PTB domain and leucine zipper motif 1
Organism-1
Human
基因ID-1
26060
SwissProt-1
Q9UKG1
Organism-2
Mouse
基因ID-2
72993
SwissProt-2
Q8K3H0
背景
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1(APPL1) Homo sapiens The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008],
细胞定位
Early endosome membrane ; Peripheral membrane protein . Nucleus . Cytoplasm . Endosome . Cell projection, ruffle . Cytoplasmic vesicle, phagosome . Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF. .
