FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ApoER2
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
100kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human LRP8. AA range:451-500
特异性
ApoER2 Polyclonal Antibody detects endogenous levels of ApoER2 protein.
基因名称
LRP8
蛋白名称
Low-density lipoprotein receptor-related protein 8
别名
LRP8;APOER2;Low-density lipoprotein receptor-related protein 8;LRP-8;Apolipoprotein E receptor 2
Organism-1
Human
基因ID-1
55911
SwissProt-1
Q14114
Organism-2
Mouse
SwissProt-2
Q924X6
背景
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Secreted . Isoforms that contain the exon coding for a furin-type cleavage site are proteolytically processed, leading to a secreted receptor fragment. .
