FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
APOBEC3A
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human APOBEC3A. AA range:27-76
特异性
APOBEC3A Polyclonal Antibody detects endogenous levels of APOBEC3A protein.
基因名称
APOBEC3A
蛋白名称
Probable DNA dC->dU-editing enzyme APOBEC-3A
别名
APOBEC3A;Probable DNA dC->dU-editing enzyme APOBEC-3A;Phorbolin-1
Organism-1
Human
基因ID-1
200315
SwissProt-1
P31941
背景
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided b
细胞定位
Nucleus. Cytoplasm.
