FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
APC5
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200
特异性
APC5 Polyclonal Antibody detects endogenous levels of APC5 protein.
基因名称
ANAPC5
蛋白名称
Anaphase-promoting complex subunit 5
别名
ANAPC5;APC5;Anaphase-promoting complex subunit 5;APC5;Cyclosome subunit 5
Organism-1
Human
基因ID-1
51433
SwissProt-1
Q9UJX4
Organism-2
Mouse
SwissProt-2
Q8BTZ4
背景
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008],
细胞定位
Nucleus . Cytoplasm, cytoskeleton, spindle .
