APBA2BP Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612819

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商品描述
  • 靶点-Target

    APBA2BP

  • 反应性

    Human,Mouse

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    44kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human NECAB3. AA range:321-370

  • 特异性

    APBA2BP Polyclonal Antibody detects endogenous levels of APBA2BP protein.

  • 基因名称

    NECAB3

  • 蛋白名称

    N-terminal EF-hand calcium-binding protein 3

  • 别名

    NECAB3;APBA2BP;NIP1;SYTIP2;XB51;N-terminal EF-hand calcium-binding protein 3;Amyloid beta A4 protein-binding family A member 2-binding protein;Nek2-interacting protein 1;Neuronal calcium-binding protein 3;X11L-binding protein 51

  • Organism-1

    Human

  • 基因ID-1

    63941

  • SwissProt-1

    Q96P71

  • Organism-2

    Mouse

  • 基因ID-2

    56846

  • SwissProt-2

    Q9D6J4

  • 背景

    The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Golgi apparatus .