- 产品信息
商品描述
靶点-Target
APBA2BP
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
44kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NECAB3. AA range:321-370
特异性
APBA2BP Polyclonal Antibody detects endogenous levels of APBA2BP protein.
基因名称
NECAB3
蛋白名称
N-terminal EF-hand calcium-binding protein 3
别名
NECAB3;APBA2BP;NIP1;SYTIP2;XB51;N-terminal EF-hand calcium-binding protein 3;Amyloid beta A4 protein-binding family A member 2-binding protein;Nek2-interacting protein 1;Neuronal calcium-binding protein 3;X11L-binding protein 51
Organism-1
Human
基因ID-1
63941
SwissProt-1
Q96P71
Organism-2
Mouse
基因ID-2
56846
SwissProt-2
Q9D6J4
背景
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Golgi apparatus .





