FGF-2 Polyclonal Antibody
¥680.00
Apaf-1-ALT Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612818
- 产品信息
商品描述
靶点-Target
APAF1
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human APAF-1-ALT. AA range:289-338
特异性
Apaf-1-ALT Polyclonal Antibody detects endogenous levels of Apaf-1-ALT protein.
基因名称
APAF1
蛋白名称
Apoptotic protease-activating factor 1
别名
APAF1-interacting protein;APIP;APIP2;CGI-29 protein;MMRP19;dJ179L10.2;likely ortholog of mouse monocyte macrophage 19
Organism-1
Human
基因ID-1
317
SwissProt-1
O14727-6
背景
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm .
