- 产品信息
商品描述
靶点-Target
ANT4
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
35kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SLC25A31. AA range:131-180
特异性
ANT4 Polyclonal Antibody detects endogenous levels of ANT4 protein.
基因名称
SLC25A31
蛋白名称
ADP/ATP translocase 4
别名
SLC25A31;AAC4;ANT4;SFEC;ADP/ATP translocase 4;ADP;ATP carrier protein 4;Adenine nucleotide translocator 4;ANT 4;Solute carrier family 25 member 31;Sperm flagellar energy carrier protein
Organism-1
Human
基因ID-1
83447
SwissProt-1
Q9H0C2
Organism-2
Mouse
基因ID-2
73333
SwissProt-2
Q3V132
背景
The protein encoded by this gene is a member of the ADP/ATP carrier family of proteins that exchange cytosolic ADP for matrix ATP in the mitochondria. Cells over-expressing this gene have been shown to display an anti-apoptotic phenotype. This protein is also thought to play a role in spermatogenesis, where it is believed to associate with a part of the flagellar cytoskeleton and with glycolytic enzymes. Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . Cell projection, cilium, flagellum membrane ; Multi-pass membrane protein . In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region (PubMed:17137571). May localize to non-mitochondrial membranes (PubMed:27641616). .





