- 产品信息
商品描述
靶点-Target
AMPD1
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
86kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human AMPD1. AA range:261-310
特异性
AMPD1 Polyclonal Antibody detects endogenous levels of AMPD1 protein.
基因名称
AMPD1
蛋白名称
AMP deaminase 1
别名
AMPD1;AMP deaminase 1;AMP deaminase isoform M;Myoadenylate deaminase
Organism-1
Human
基因ID-1
270
SwissProt-1
P23109
Organism-2
Mouse
SwissProt-2
Q3V1D3
Organism-3
Rat
基因ID-3
25028
SwissProt-3
P10759
背景
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010],
细胞定位
cytosol,





