- 产品信息
商品描述
靶点-Target
ALY
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human THOC4. AA range:121-170
特异性
ALY Polyclonal Antibody detects endogenous levels of ALY protein.
基因名称
ALYREF
蛋白名称
THO complex subunit 4
别名
ALYREF;ALY;BEF;THOC4;THO complex subunit 4;Tho4;Ally of AML-1 and LEF-1;Aly/REF export factor;Transcriptional coactivator Aly/REF;bZIP-enhancing factor BEF
Organism-1
Human
基因ID-1
10189
SwissProt-1
Q86V81
Organism-2
Mouse
基因ID-2
21681
SwissProt-2
O08583
背景
The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus speckle . Cytoplasm . Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and DDX39B in the nucleus and nuclear speckles. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA (PubMed:19324961). Localizes to regions surrounding nuclear speckles known as perispeckles in which TREX complex assembly seems to occur (PubMed:23826332). .





