Aldose Reductase Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612769

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商品描述
  • 靶点-Target

    AKR1B1

  • 反应性

    Human,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    36kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human AKR1B1. AA range:241-290

  • 特异性

    Aldose Reductase Polyclonal Antibody detects endogenous levels of Aldose Reductase protein.

  • 基因名称

    AKR1B1

  • 蛋白名称

    Aldose reductase

  • 别名

    AKR1B1;ALDR1;Aldose reductase;AR;Aldehyde reductase;Aldo-keto reductase family 1 member B1

  • Organism-1

    Human

  • 基因ID-1

    231

  • SwissProt-1

    P15121

  • Organism-2

    Mouse

  • SwissProt-2

    P45376

  • Organism-3

    Rat

  • 基因ID-3

    24192

  • SwissProt-3

    P07943

  • 背景

    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009],

  • 细胞定位

    Cytoplasm.