FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AKAP 79
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
47kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human AKAP5. AA range:1-50
特异性
AKAP 79 Polyclonal Antibody detects endogenous levels of AKAP 79 protein.
基因名称
AKAP5
蛋白名称
A-kinase anchor protein 5
别名
AKAP5;AKAP79;A-kinase anchor protein 5;AKAP-5;A-kinase anchor protein 79 kDa;AKAP 79;H21;cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein
Organism-1
Human
基因ID-1
9495
SwissProt-1
P24588
Organism-2
Mouse
SwissProt-2
D3YVF0
背景
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008],
细胞定位
Postsynaptic recycling endosome membrane ; Lipid-anchor . Associates with lipid rafts. .
