- 产品信息
商品描述
靶点-Target
AKAP 220
反应性
Human,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
211kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human AKAP11. AA range:1761-1810
特异性
AKAP 220 Polyclonal Antibody detects endogenous levels of AKAP 220 protein.
基因名称
AKAP11
蛋白名称
A-kinase anchor protein 11
别名
AKAP11;AKAP220;KIAA0629;A-kinase anchor protein 11;AKAP-11;A-kinase anchor protein 220 kDa;AKAP 220;hAKAP220;Protein kinase A-anchoring protein 11;PRKA11
Organism-1
Human
基因ID-1
11215
SwissProt-1
Q9UKA4
背景
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic in premeiotic pachytene spermatocytes and in the centrosome of developing postmeiotic germ cells, while a midpiece/centrosome localization was found in elongating spermatocytes and mature sperm.





