Adenosine A2A-R Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612719
- 产品信息
商品描述
靶点-Target
Adenosine A2A-R
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
37kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ADORA2A. AA range:120-169
特异性
Adenosine A2A-R Polyclonal Antibody detects endogenous levels of Adenosine A2A-R protein.
基因名称
ADORA2A
蛋白名称
Adenosine receptor A2a
别名
ADORA2A;ADORA2;Adenosine receptor A2a
Organism-1
Human
基因ID-1
135
SwissProt-1
P29274
Organism-2
Mouse
SwissProt-2
Q60613
背景
adenosine A2a receptor(ADORA2A) Homo sapiens This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript compos
细胞定位
Cell membrane ; Multi-pass membrane protein . Colocalizes with GAS2L2 at neuronal processes. .





