FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ADAR1
反应性
Human,Mouse,Rat
应用
IHC,IF,WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
135kD
推荐稀释比
WB 1:500-2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ADAR1. AA range:1172-1221
特异性
ADAR1 Polyclonal Antibody detects endogenous levels of ADAR1 protein.
基因名称
ADAR
蛋白名称
Double-stranded RNA-specific adenosine deaminase
别名
ADAR;ADAR1;DSRAD;G1P1;IFI4;Double-stranded RNA-specific adenosine deaminase;DRADA;136 kDa double-stranded RNA-binding protein;p136;Interferon-inducible protein 4;IFI-4;K88DSRBP
Organism-1
Human
基因ID-1
103
SwissProt-1
P55265
Organism-2
Mouse
基因ID-2
56417
SwissProt-2
Q99MU3
Organism-3
Rat
基因ID-3
81635
SwissProt-3
P55266
背景
adenosine deaminase, RNA specific(ADAR) Homo sapiens This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010],
细胞定位
[Isoform 1]: Cytoplasm . Nucleus . Shuttles between the cytoplasm and nucleus (PubMed:7565688, PubMed:24753571). Nuclear import is mediated by TNPO1 (PubMed:24753571). .; [Isoform 5]: Cytoplasm . Nucleus . Nucleus, nucleolus . Predominantly nuclear but can shuttle between nucleus and cytoplasm. TNPO1 can mediate its nuclear import whereas XPO5 can mediate its nuclear export. .
