FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ACTR-IC
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
55kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ACTR-1C. AA range:201-250
特异性
ACTR-IC Polyclonal Antibody detects endogenous levels of ACTR-IC protein.
基因名称
ACVR1C
蛋白名称
Activin receptor type-1C
别名
ACVR1C;ALK7;Activin receptor type-1C;Activin receptor type IC;ACTR-IC;Activin receptor-like kinase 7;ALK-7
Organism-1
Human
基因ID-1
130399
SwissProt-1
Q8NER5
Organism-2
Mouse
基因ID-2
269275
SwissProt-2
Q8K348
Organism-3
Rat
基因ID-3
245921
SwissProt-3
P70539
背景
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008],
细胞定位
Membrane ; Single-pass type I membrane protein .
