ACTR-IB Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612696

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商品描述
  • 靶点-Target

    ACTR-IB

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    56kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ACV1B. AA range:73-122

  • 特异性

    ACTR-IB Polyclonal Antibody detects endogenous levels of ACTR-IB protein.

  • 基因名称

    ACVR1B

  • 蛋白名称

    Activin receptor type-1B

  • 别名

    ACVR1B;ACVRLK4;ALK4;Activin receptor type-1B;Activin receptor type IB;ACTR-IB;Activin receptor-like kinase 4;ALK-4;Serine/threonine-protein kinase receptor R2;SKR2

  • Organism-1

    Human

  • 基因ID-1

    91

  • SwissProt-1

    P36896

  • Organism-2

    Mouse

  • 基因ID-2

    11479

  • SwissProt-2

    Q61271

  • Organism-3

    Rat

  • 基因ID-3

    29381

  • SwissProt-3

    P80202

  • 背景

    This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010],

  • 细胞定位

    Cell membrane ; Single-pass type I membrane protein .