- 产品信息
商品描述
靶点-Target
ACTR-IB
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
56kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ACV1B. AA range:73-122
特异性
ACTR-IB Polyclonal Antibody detects endogenous levels of ACTR-IB protein.
基因名称
ACVR1B
蛋白名称
Activin receptor type-1B
别名
ACVR1B;ACVRLK4;ALK4;Activin receptor type-1B;Activin receptor type IB;ACTR-IB;Activin receptor-like kinase 4;ALK-4;Serine/threonine-protein kinase receptor R2;SKR2
Organism-1
Human
基因ID-1
91
SwissProt-1
P36896
Organism-2
Mouse
基因ID-2
11479
SwissProt-2
Q61271
Organism-3
Rat
基因ID-3
29381
SwissProt-3
P80202
背景
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010],
细胞定位
Cell membrane ; Single-pass type I membrane protein .





