- 产品信息
商品描述
靶点-Target
AChRα3
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human AChRalpha3. AA range:90-139
特异性
AChRα3 Polyclonal Antibody detects endogenous levels of AChRα3 protein.
基因名称
CHRNA3
蛋白名称
Neuronal acetylcholine receptor subunit alpha-3
别名
CHRNA3;NACHRA3;Neuronal acetylcholine receptor subunit alpha-3
Organism-1
Human
基因ID-1
1136
SwissProt-1
P32297
Organism-2
Mouse
基因ID-2
110834
SwissProt-2
Q8R4G9
Organism-3
Rat
SwissProt-3
P04757
背景
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009],
细胞定位
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein.





