FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ACCα
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
265kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ACC1. AA range:46-95
特异性
ACCα Polyclonal Antibody detects endogenous levels of ACCα protein.
基因名称
ACACA
蛋白名称
Acetyl-CoA carboxylase 1
别名
ACACA;ACAC;ACC1;ACCA;Acetyl-CoA carboxylase 1;ACC1;ACC-alpha
Organism-1
Human
基因ID-1
31
SwissProt-1
Q13085
Organism-2
Mouse
基因ID-2
107476
SwissProt-2
Q5SWU9
Organism-3
Rat
基因ID-3
60581
SwissProt-3
P11497
背景
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytosol .
