- 产品信息
商品描述
靶点-Target
ABHD7
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ABHD7. AA range:101-150
特异性
ABHD7 Polyclonal Antibody detects endogenous levels of ABHD7 protein.
基因名称
EPHX4
蛋白名称
Epoxide hydrolase 4
别名
EPHX4;ABHD7;EPHXRP;Epoxide hydrolase 4;Abhydrolase domain-containing protein 7;Epoxide hydrolase-related protein
Organism-1
Human
基因ID-1
253152
SwissProt-1
Q8IUS5
Organism-2
Mouse
基因ID-2
384214
SwissProt-2
Q6IE26
背景
The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight-stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD7 is a 362 amino acid single-pass type II membrane protein that belongs to the AB hydrolase superfamily and the Epoxide hydrolase family.
细胞定位
Membrane ; Single-pass type II membrane protein .





