- 产品信息
商品描述
靶点-Target
ABHD4
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
39kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ABHD4. AA range:251-300
特异性
ABHD4 Polyclonal Antibody detects endogenous levels of ABHD4 protein.
基因名称
ABHD4
蛋白名称
Abhydrolase domain-containing protein 4
别名
ABHD4;Abhydrolase domain-containing protein 4;Alpha/beta-hydrolase 4;Lyso-N-acylphosphatidylethanolamine lipase
Organism-1
Human
基因ID-1
63874
SwissProt-1
Q8TB40
Organism-2
Mouse
基因ID-2
105501
SwissProt-2
Q8VD66
背景
caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue.,function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.,similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.,
细胞定位
endoplasmic reticulum membrane,lipid particle,





