FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ABHD12
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ABHD12. AA range:231-280
特异性
ABHD12 Polyclonal Antibody detects endogenous levels of ABHD12 protein.
基因名称
ABHD12
蛋白名称
Monoacylglycerol lipase ABHD12
别名
ABHD12;C20orf22;Monoacylglycerol lipase ABHD12;2-arachidonoylglycerol hydrolase;Abhydrolase domain-containing protein 12
Organism-1
Human
基因ID-1
26090
SwissProt-1
Q8N2K0
Organism-2
Mouse
基因ID-2
76192
SwissProt-2
Q99LR1
Organism-3
Rat
基因ID-3
499913
SwissProt-3
Q6AYT7
背景
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011],
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .
