FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ABCB7
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
Human:83kD,Mouse/Rat:100kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ABCB7. AA range:691-740
特异性
ABCB7 Polyclonal Antibody detects endogenous levels of ABCB7 protein.
基因名称
ABCB7
蛋白名称
ATP-binding cassette sub-family B member 7 mitochondrial
别名
ABCB7;ABC7;ATP-binding cassette sub-family B member 7;mitochondrial;ATP-binding cassette transporter 7;ABC transporter 7 protein
Organism-1
Human
基因ID-1
22
SwissProt-1
O75027
Organism-2
Mouse
SwissProt-2
Q61102
背景
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms hav
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .
