FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
A1Up
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
54kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human UBQLN4. AA range:201-250
特异性
A1Up Polyclonal Antibody detects endogenous levels of A1Up protein.
基因名称
UBQLN4
蛋白名称
Ubiquilin-4
别名
UBQLN4;C1orf6;CIP75;UBIN;Ubiquilin-4;Ataxin-1 interacting ubiquitin-like protein;A1Up;Ataxin-1 ubiquitin-like-interacting protein A1U;Connexin43-interacting protein of 75 kDa;CIP75
Organism-1
Human
基因ID-1
56893
SwissProt-1
Q9NRR5
Organism-2
Mouse
基因ID-2
94232
SwissProt-2
Q99NB8
背景
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 UBA domain.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:May associate with the endoplasmic reticulum.,subunit:Homodimer. Binds SCA1. Binds signal sequences of proteins that are targeted to the endoplasmic reticulum.,tissue specificity:Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.,
细胞定位
Nucleus . Cytoplasm . Chromosome . Endoplasmic reticulum . Cytoplasm, perinuclear region . Cytoplasmic vesicle, autophagosome . Colocalizes with the proteasome, both in nucleus and cytoplasm (PubMed:15280365). Exported from the nucleus following interaction with DESI1/POST (PubMed:29666234). In response to DNA damage and phosphorylation at Ser-318 by ATM, localizes to the nucleus and is recruited to sites of DNA damage (PubMed:30612738). .
