A Cyclase V/VI Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612623
- 产品信息
商品描述
靶点-Target
A Cyclase V/VI
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
138kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ADCY5/6. AA range:931-980
特异性
A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein.
基因名称
ADCY5/ADCY6
蛋白名称
Adenylate cyclase type 5/6
别名
ADCY5;Adenylate cyclase type 5;ATP pyrophosphate-lyase 5;Adenylate cyclase type V;Adenylyl cyclase 5;ADCY6;KIAA0422;Adenylate cyclase type 6;ATP pyrophosphate-lyase 6;Adenylate cyclase type VI;Adenylyl cyclase 6;Ca;2+;-inhibitabl
Organism-1
Human
基因ID-1
111;112
SwissProt-1
O95622;O43306
Organism-2
Mouse
基因ID-2
224129;11512
Organism-3
Rat
基因ID-3
64532
SwissProt-3
Q04400;Q03343
背景
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
细胞定位
Cell membrane ; Multi-pass membrane protein. Cell projection, cilium .





