FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
3β-HSD7
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
41kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HSD3B7. AA range:121-170
特异性
3β-HSD7 Polyclonal Antibody detects endogenous levels of 3β-HSD7 protein.
基因名称
HSD3B7
蛋白名称
3 beta-hydroxysteroid dehydrogenase type 7
别名
HSD3B7;3 beta-hydroxysteroid dehydrogenase type 7;3 beta-hydroxysteroid dehydrogenase type VII;3-beta-HSD VII;3-beta-hydroxy-Delta;5;-C27 steroid oxidoreductase;C;27;3-beta-HSD;Cholest-5-ene-3-beta;7-alpha-diol 3-beta-dehydrogenase
Organism-1
Human
基因ID-1
80270
SwissProt-1
Q9H2F3
Organism-2
Mouse
基因ID-2
101502
SwissProt-2
Q9EQC1
Organism-3
Rat
基因ID-3
246211
SwissProt-3
O35048
背景
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
细胞定位
Endoplasmic reticulum membrane; Multi-pass membrane protein.
