FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
14-3-3 ε
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
29kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human 14-3-3 epsilon. AA range:206-255
特异性
14-3-3 ε Polyclonal Antibody detects endogenous levels of 14-3-3 ε protein.
基因名称
YWHAE
蛋白名称
14-3-3 protein epsilon
别名
YWHAE;14-3-3 protein epsilon;14-3-3E
Organism-1
Human
基因ID-1
7531
SwissProt-1
P62258
Organism-2
Mouse
基因ID-2
22627
SwissProt-2
P62259
Organism-3
Rat
基因ID-3
29753
SwissProt-3
P62260
背景
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008],
细胞定位
Nucleus . Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
