CaMKIIβ/γ/δ (Phospho Thr287) Monoclonal Antibody(4H2)

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¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2612590

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商品描述
  • 靶点-Target

    CaMKIIβ/γ/δ

  • 反应性

    Human,Rat,Mouse

  • 应用

    IHC,IF

  • 宿主物种-Host Species

    Mouse

  • 修饰-Modification

    Phospho

  • MW(Observed)

    50kD

  • 推荐稀释比

    IHC 1:100-200;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Monoclonal

  • 克隆号

    4H2

  • 免疫原

    Synthetic Peptide of CaMKIIβ/γ/δ (Phospho Thr287)

  • 特异性

    CaMKIIβ/γ/δ (Phospho Thr287) protein detects endogenous levels of CaMKIIβ/γ/δ (Phospho Thr287)

  • 别名

    CAMK2B;CAM2;CAMK2;CAMKB;Calcium/calmodulin-dependent protein kinase type II subunit beta;CaM kinase II subunit beta;CaMK-II subunit beta;CAMK2G;CAMK;CAMK-II;CAMKG;Calcium/calmodulin-dependent protein kinase type II subunit gamma;

  • Organism-1

    Human

  • 基因ID-1

    816;817;818

  • SwissProt-1

    Q13554;Q13555;Q13557

  • 背景

    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

  • 细胞定位

    Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse . In slow-twitch muscle, evenly distributed between longitudinal SR and junctional SR.