FGF-2 Polyclonal Antibody
¥680.00
Lamin A/C (phospho Ser392) (PTR1133) mouse mAb
活动价：
¥880.00
市场价：¥1280.00
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产品规格：
- 50μL
货号：
FAB2612586
- 产品信息
商品描述
靶点-Target
Lamin A/C (phospho Ser392)
反应性
Human,Mouse,Rat,Monkey,
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
同种型-Isotype
IgG1,Kappa
修饰-Modification
Phospho
MW(Calculated)
63kD,74kD
MW(Observed)
63kD,74kD
推荐稀释比
WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
Protein G
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Monoclonal
克隆号
PTR1133
免疫原
Synthesized peptide derived from human protein. AA range: 350-450
特异性
This antibody detects endogenous levels of Lamin A/C (phospho Ser392) protein.
基因名称
LMNA LMN1
蛋白名称
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
别名
Prelamin-A/C [Cleaved into: Lamin-A/C;70 kDa lamin;Renal carcinoma antigen NY-REN-32;]
Organism-1
Human
基因ID-1
4000
SwissProt-1
P02545
Organism-2
Mouse
基因ID-2
16905
SwissProt-2
P48678
背景
lamin A/C(LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012],
