FGF-2 Polyclonal Antibody
¥680.00
FGFR4 (Phospho Tyr754) Rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612585
- 产品信息
商品描述
靶点-Target
FGFR-4
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Observed)
90kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FGFR4 (Phospho Tyr754)
特异性
This antibody detects endogenous levels of FGFR4 (Phospho Tyr754) Rabbit pAb at Human, Mouse,Rat
基因名称
FGFR4 JTK2 TKF
蛋白名称
Fibroblast growth factor receptor 4 (FGFR-4) (CD antigen CD334)
别名
Fibroblast growth factor receptor 4;FGFR-4;CD antigen CD334;
Organism-1
Human
基因ID-1
2264
SwissProt-1
P22455
Organism-2
Mouse
基因ID-2
14186
SwissProt-2
Q03142
Organism-3
Rat
基因ID-3
25114
SwissProt-3
Q498D6
背景
fibroblast growth factor receptor 4(FGFR4) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgII
细胞定位
Cell membrane; Single-pass type I membrane protein. Endosome. Endoplasmic reticulum. Internalized from the cell membrane to recycling endosomes, and from there back to the cell membrane.; [Isoform 2]: Secreted.; [Isoform 3]: Cytoplasm .
