PFK-2 car (Phospho Ser466) Rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612582
- 产品信息
商品描述
靶点-Target
PFK-2 car
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Observed)
58kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PFKFB2 (Phospho Ser466)
特异性
This antibody detects endogenous levels of PFKFB2 (Phospho Ser466) Rabbit pAb at Human, Mouse,Rat
基因名称
PFKFB2
蛋白名称
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]
别名
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6PF-2-K/Fru-2,6-P2ase 2;PFK/FBPase 2;6PF-2-K/Fru-2,6-P2ase heart-type isozyme;[Includes: 6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase;]
Organism-1
Human
基因ID-1
5208
SwissProt-1
O60825
Organism-2
Mouse
基因ID-2
18640
SwissProt-2
P70265
Organism-3
Rat
基因ID-3
24640
SwissProt-3
Q9JJH5
背景
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2(PFKFB2) Homo sapiens The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],





