FGF-2 Polyclonal Antibody
¥680.00
Ret (Phospho Tyr1096) Rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612579
- 产品信息
商品描述
靶点-Target
Ret
反应性
Human,Mouse
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Calculated)
123kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Ret (Phospho Tyr1096)
特异性
This antibody detects endogenous levels of Ret (Phospho Tyr1096) Rabbit pAb at Human, Mouse
基因名称
RET CDHF12 CDHR16 PTC RET51
蛋白名称
Proto-oncogene tyrosine-protein kinase receptor Ret (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
别名
Proto-oncogene tyrosine-protein kinase receptor Ret;Cadherin family member 12;Proto-oncogene c-Ret;[Cleaved into: Soluble RET kinase fragment;Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Organism-1
Human
基因ID-1
5979
SwissProt-1
P07949
Organism-2
Mouse
基因ID-2
19713
SwissProt-2
P35546
背景
ret proto-oncogene(RET) Homo sapiens This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Predominantly located on the plasma membrane. In the presence of SORL1 and GFRA1, directed to endosomes. .
