GAB2 (Phospho Tyr614) Rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612577
- 产品信息
商品描述
靶点-Target
Gab2
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Observed)
100kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human GAB2 (Phospho Tyr614)
特异性
This antibody detects endogenous levels of GAB2 (Phospho Tyr614) Rabbit pAb at Human, Mouse,Rat
基因名称
GAB2 KIAA0571
蛋白名称
GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100)
别名
GRB2-associated-binding protein 2;GRB2-associated binder 2;Growth factor receptor bound protein 2-associated protein 2;pp100;
Organism-1
Human
基因ID-1
9846
SwissProt-1
Q9UQC2
Organism-2
Mouse
SwissProt-2
Q9Z1S8
Organism-3
Rat
基因ID-3
84477
SwissProt-3
Q9EQH1
背景
GRB2 associated binding protein 2(GAB2) Homo sapiens This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009],
细胞定位
Cytoplasm . Cell membrane .





