FGF-2 Polyclonal Antibody
¥680.00
PRC1 (Phospho Thr470) Rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612573
- 产品信息
商品描述
靶点-Target
PRC1
反应性
Human,Mouse
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Observed)
72kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PRC1 (Phospho Thr470)
特异性
This antibody detects endogenous levels of PRC1 (Phospho Thr470) Rabbit pAb at Human, Mouse
基因名称
PRC1
蛋白名称
Protein regulator of cytokinesis 1
别名
Protein regulator of cytokinesis 1
Organism-1
Human
基因ID-1
9055
SwissProt-1
O43663
Organism-2
Mouse
基因ID-2
233406
SwissProt-2
Q99K43
背景
protein regulator of cytokinesis 1(PRC1) Homo sapiens This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012],
细胞定位
Nucleus . Cytoplasm. Cytoplasm, cytoskeleton, spindle pole . Midbody . Chromosome . Colocalized with KIF20B in the nucleus of bladder carcinoma cells at the interphase. Colocalized with KIF20B in bladder carcinoma cells at prophase, metaphase, early anaphase, at the midzone in late anaphase and at the contractile ring in telophase (PubMed:17409436). Predominantly localized to the nucleus of interphase cells. During mitosis becomes associated with the mitotic spindle poles and localizes with the cell midbody during cytokinesis. Co-localizes with PRC1 in early mitosis and at the spindle midzone from anaphase B to telophase (PubMed:15297875, PubMed:15625105). .
