STAT4 (Phospho Ser721) Rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612567
- 产品信息
商品描述
靶点-Target
Stat4
反应性
Human,Mouse
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Observed)
86kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human STAT4 (Phospho Ser721)
特异性
This antibody detects endogenous levels of STAT4 (Phospho Ser721) Rabbit pAb at Human, Mouse
基因名称
STAT4
蛋白名称
Signal transducer and activator of transcription 4
别名
Signal transducer and activator of transcription 4
Organism-1
Human
基因ID-1
6775
SwissProt-1
Q14765
Organism-2
Mouse
基因ID-2
20849
SwissProt-2
P42228
背景
signal transducer and activator of transcription 4(STAT4) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],
细胞定位
Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.





