Met (Phospho Tyr1313) Rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612549

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商品描述
  • 靶点-Target

    Met

  • 反应性

    Human,Mouse,Rat

  • 应用

    IHC,WB

  • 宿主物种-Host Species

    Rabbit

  • 修饰-Modification

    Phospho

  • MW(Observed)

    155kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-200

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human Met (Phospho Tyr1313)

  • 特异性

    This antibody detects endogenous levels of Met (Phospho Tyr1313) Rabbit pAb at Human, Mouse,Rat

  • 基因名称

    MET

  • 蛋白名称

    Hepatocyte growth factor receptor (HGF receptor) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)

  • 别名

    Hepatocyte growth factor receptor;HGF receptor;HGF/SF receptor;Proto-oncogene c-Met;Scatter factor receptor;SF receptor;Tyrosine-protein kinase Met;

  • Organism-1

    Human

  • 基因ID-1

    4233

  • SwissProt-1

    P08581

  • Organism-2

    Mouse

  • SwissProt-2

    P16056

  • Organism-3

    Rat

  • 基因ID-3

    24553

  • SwissProt-3

    P97523

  • 背景

    MET proto-oncogene, receptor tyrosine kinase(MET) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016],

  • 细胞定位

    Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.