FGF-2 Polyclonal Antibody
¥680.00
HDAC7A (Phospho Ser486) Rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612542
- 产品信息
商品描述
靶点-Target
HDAC7
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Observed)
103kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human HDAC7A (Phospho Ser486)
特异性
This antibody detects endogenous levels of HDAC7A (Phospho Ser486) Rabbit pAb at Human, Mouse,Rat
基因名称
HDAC7 HDAC7A
蛋白名称
Histone deacetylase 7 (HD7) (Histone deacetylase 7A) (HD7a)
别名
Histone deacetylase 7;HD7;Histone deacetylase 7A;HD7a;
Organism-1
Human
基因ID-1
51564
SwissProt-1
Q8WUI4
Organism-2
Mouse
基因ID-2
56233
SwissProt-2
Q8C2B3
Organism-3
Rat
SwissProt-3
Q99P96
背景
histone deacetylase 7(HDAC7) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Cytoplasm. In the nucleus, it associates with distinct subnuclear dot-like structures. Shuttles between the nucleus and the cytoplasm. Treatment with EDN1 results in shuttling from the nucleus to the perinuclear region. The export to cytoplasm depends on the interaction with the 14-3-3 protein YWHAE and is due to its phosphorylation.
