FGF-2 Polyclonal Antibody
¥680.00
EPHA2 (Phospho Tyr930) Rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612529
- 产品信息
商品描述
靶点-Target
EphA2
反应性
Human,Mouse
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Observed)
130kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human EPHA2 (Phospho Tyr930)
特异性
This antibody detects endogenous levels of EPHA2 (Phospho Tyr930) Rabbit pAb at Human, Mouse
基因名称
EPHA2 ECK
蛋白名称
Ephrin type-A receptor 2 (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
别名
Ephrin type-A receptor 2;Epithelial cell kinase;Tyrosine-protein kinase receptor ECK;
Organism-1
Human
基因ID-1
1969
SwissProt-1
P29317
Organism-2
Mouse
基因ID-2
13836
SwissProt-2
Q03145
背景
EPH receptor A2(EPHA2) Homo sapiens This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell projection, ruffle membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell junction, focal adhesion . Present at regions of cell-cell contacts but also at the leading edge of migrating cells (PubMed:19573808, PubMed:20861311). Relocates from the plasma membrane to the cytoplasmic and perinuclear regions in cancer cells (PubMed:18794797). .
