Bcl-6 (Phospho Ser343) Rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612519
- 产品信息
商品描述
靶点-Target
Bcl-6
反应性
Human,Mouse
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Observed)
80kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Bcl-6 (Phospho Ser343)
特异性
This antibody detects endogenous levels of Bcl-6 (Phospho Ser343) Rabbit pAb at Human, Mouse
基因名称
BCL6 BCL5 LAZ3 ZBTB27 ZNF51
蛋白名称
B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51)
别名
B-cell lymphoma 6 protein;BCL-6;B-cell lymphoma 5 protein;BCL-5;Protein LAZ-3;Zinc finger and BTB domain-containing protein 27;Zinc finger protein 51;
Organism-1
Human
基因ID-1
604
SwissProt-1
P41182
Organism-2
Mouse
基因ID-2
12053
SwissProt-2
P41183
背景
B-cell CLL/lymphoma 6(BCL6) Homo sapiens The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015],
细胞定位
Nucleus .





