FGF-2 Polyclonal Antibody
¥680.00
Leptin Receptor (Phospho Tyr986) Rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612517
- 产品信息
商品描述
靶点-Target
Ob-R
反应性
Human,Mouse,Rat
应用
IHC,WB
宿主物种-Host Species
Rabbit
修饰-Modification
Phospho
MW(Observed)
132kD
推荐稀释比
WB 1:500-2000;IHC 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Leptin Receptor (Phospho Tyr986)
特异性
This antibody detects endogenous levels of Leptin Receptor (Phospho Tyr986) Rabbit pAb at Human, Mouse,Rat
基因名称
LEPR DB OBR
蛋白名称
Leptin receptor (LEP-R) (HuB219) (OB receptor) (OB-R) (CD antigen CD295)
别名
Leptin receptor;LEP-R;HuB219;OB receptor;OB-R;CD antigen CD295;
Organism-1
Human
基因ID-1
3953
SwissProt-1
P48357
Organism-2
Mouse
基因ID-2
16847
SwissProt-2
P48356
Organism-3
Rat
基因ID-3
24536
SwissProt-3
Q62959
背景
leptin receptor(LEPR) Homo sapiens The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Basolateral cell membrane .; [Isoform E]: Secreted .
