GRK1/2 (Phospho Tyr13) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612501
- 产品信息
商品描述
靶点-Target
GRK1/2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
76kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human GRK1/2 (Phospho-Tyr13)
特异性
This antibody detects endogenous levels of GRK1/2 (Phospho-Tyr13) at Human, Mouse,Rat
基因名称
ADRBK1 BARK BARK1 GRK2
蛋白名称
GRK1/2 (Phospho-Tyr13)
别名
Beta-adrenergic receptor kinase 1;Beta-ARK-1;G-protein coupled receptor kinase 2;
Organism-1
Human
基因ID-1
156
SwissProt-1
P25098
Organism-2
Mouse
SwissProt-2
Q99MK8
Organism-3
Rat
基因ID-3
25238
SwissProt-3
P26817
背景
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Cell membrane . Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .





