FGF-2 Polyclonal Antibody
¥680.00
Retinoic Acid Receptor α/β (Phospho Ser96) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612492
- 产品信息
商品描述
靶点-Target
Retinoic Acid Receptor α/β
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Observed)
50kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Retinoic Acid Receptor α/β (Phospho-Ser96)
特异性
This antibody detects endogenous levels of Retinoic Acid Receptor α/β (Phospho-Ser96) at Human, Mouse,Rat
基因名称
RARA NR1B1
蛋白名称
Retinoic Acid Receptor α/β (Phospho-Ser96)
别名
Retinoic acid receptor alpha;RAR-alpha;Nuclear receptor subfamily 1 group B member 1;
Organism-1
Human
基因ID-1
5914
SwissProt-1
P10276
Organism-2
Mouse
基因ID-2
19401
SwissProt-2
P11416
背景
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010],
细胞定位
Nucleus . Cytoplasm . Nuclear localization depends on ligand binding, phosphorylation and sumoylation (PubMed:19850744). Translocation to the nucleus in the absence of ligand is dependent on activation of PKC and the downstream MAPK phosphorylation (By similarity). Increased nuclear localization upon pulsatile shear stress (PubMed:28167758). .
