Ataxin-3 (Phospho Ser256) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612478
- 产品信息
商品描述
靶点-Target
Ataxin-3
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
40kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Ataxin-3 (Phospho-Ser256)
特异性
This antibody detects endogenous levels of Ataxin-3 (Phospho-Ser256) at Human, Mouse,Rat
基因名称
ATXN3 ATX3 MJD MJD1 SCA3
蛋白名称
Ataxin-3 (Phospho-Ser256)
别名
Ataxin-3;Machado-Joseph disease protein 1;Spinocerebellar ataxia type 3 protein;
Organism-1
Human
基因ID-1
4287
SwissProt-1
P54252
Organism-2
Mouse
基因ID-2
110616
SwissProt-2
Q9CVD2
Organism-3
Rat
基因ID-3
60331
SwissProt-3
O35815
背景
ataxin 3(ATXN3) Homo sapiens Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016],
细胞定位
Nucleus matrix . Nucleus . Predominantly nuclear, but not exclusively, inner nuclear matrix.





