FGF-2 Polyclonal Antibody
¥680.00
MKP-3 (Phospho Ser197) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612460
- 产品信息
商品描述
靶点-Target
MKP-3
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
42kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human MKP-3 (Phospho-Ser197)
特异性
This antibody detects endogenous levels of MKP-3 (Phospho-Ser197) at Human, Mouse,Rat
基因名称
DUSP6 MKP3 PYST1
蛋白名称
MKP-3 (Phospho-Ser197)
别名
Dual specificity protein phosphatase 6;EC 3.1.3.48;Dual specificity protein phosphatase PYST1;Mitogen-activated protein kinase phosphatase 3;MAP kinase phosphatase 3;MKP-3;
Organism-1
Human
基因ID-1
1848
SwissProt-1
Q16828
Organism-2
Mouse
基因ID-2
67603
SwissProt-2
Q9DBB1
Organism-3
Rat
基因ID-3
116663
SwissProt-3
Q64346
背景
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in t
细胞定位
Cytoplasm .
