XRCC1 (Phospho Thr284) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612456
- 产品信息
商品描述
靶点-Target
XRCC1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
70kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human XRCC1 (Phospho-Thr284)
特异性
This antibody detects endogenous levels of XRCC1 (Phospho-Thr284) at Human, Mouse,Rat
基因名称
XRCC1
蛋白名称
XRCC1 (Phospho-Thr284)
别名
DNA repair protein XRCC1;X-ray repair cross-complementing protein 1;
Organism-1
Human
基因ID-1
7515
SwissProt-1
P18887
Organism-2
Mouse
基因ID-2
22594
SwissProt-2
Q60596
Organism-3
Rat
基因ID-3
84495
SwissProt-3
Q9ESZ0
背景
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .





