FGF-2 Polyclonal Antibody
¥680.00
TLR3 (Phospho Tyr759) rabbit pAb
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2612451
- 产品信息
商品描述
靶点-Target
TLR3
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
99kD
MW(Observed)
120-140，75kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TLR3 (Phospho-Tyr759)
特异性
This antibody detects endogenous levels of TLR3 (Phospho-Tyr759) at Human, Mouse,Rat
基因名称
TLR3
蛋白名称
TLR3 (Phospho-Tyr759)
别名
Toll-like receptor 3;CD antigen CD283;
Organism-1
Human
基因ID-1
7098
SwissProt-1
O15455
Organism-2
Mouse
基因ID-2
142980
SwissProt-2
Q99MB1
背景
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate
细胞定位
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome membrane. Early endosome .
