PDE3A (Phospho Ser312) rabbit pAb
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2612449
- 产品信息
商品描述
靶点-Target
PDE3A
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Phospho
MW(Calculated)
126kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PDE3A (Phospho-Ser312)
特异性
This antibody detects endogenous levels of PDE3A (Phospho-Ser312) at Human, Mouse,Rat
基因名称
PDE3A
蛋白名称
PDE3A (Phospho-Ser312)
别名
cGMP-inhibited 3',5'-cyclic phosphodiesterase A;Cyclic GMP-inhibited phosphodiesterase A;CGI-PDE A;
Organism-1
Human
基因ID-1
5139
SwissProt-1
Q14432
Organism-2
Mouse
基因ID-2
54611
SwissProt-2
Q9Z0X4
Organism-3
Rat
基因ID-3
50678
SwissProt-3
Q62865
背景
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
细胞定位
Membrane ; Multi-pass membrane protein . Cytoplasm, cytosol .





