DYRK2/4 (Phospho Tyr382/264) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612448

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商品描述
  • 靶点-Target

    DYRK2/4

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    66kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human DYRK2/4 (Phospho-Tyr382/264)

  • 特异性

    This antibody detects endogenous levels of DYRK2/4 (Phospho-Tyr382/264) at Human, Mouse,Rat

  • 基因名称

    DYRK2

  • 蛋白名称

    DYRK2/4 (Phospho-Tyr382/264)

  • 别名

    Dual specificity tyrosine-phosphorylation-regulated kinase 2;

  • Organism-1

    Human

  • 基因ID-1

    8445

  • SwissProt-1

    Q92630

  • Organism-2

    Mouse

  • 基因ID-2

    69181

  • SwissProt-2

    Q5U4C9

  • 背景

    DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasm. Nucleus. Translocates into the nucleus following DNA damage.