TIE1 (Phospho Tyr1117) rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2612443

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商品描述
  • 靶点-Target

    TIE1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Phospho

  • MW(Calculated)

    125kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human TIE1 (Phospho-Tyr1117)

  • 特异性

    This antibody detects endogenous levels of TIE1 (Phospho-Tyr1117) at Human, Mouse,Rat

  • 基因名称

    TIE1 TIE

  • 蛋白名称

    TIE1 (Phospho-Tyr1117)

  • 别名

    Tyrosine-protein kinase receptor Tie-1;

  • Organism-1

    Human

  • 基因ID-1

    7075

  • SwissProt-1

    P35590

  • Organism-2

    Mouse

  • 基因ID-2

    21846

  • SwissProt-2

    Q06806

  • 背景

    This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

  • 细胞定位

    Cell membrane ; Single-pass type I membrane protein .